Erythema multiforme during cytomegalovirus infection and oral therapy with terbinafine: A virus-drug interaction

Abstract

The authors report a case of erythema multiforme in a 32-year-old woman who was also taking oral terbinafine for an onychomycosis. The patient data analysis showed serological positivity for cytomegalovirus (Igm and IgG) and hepatitis C virus and serological titre of antinuclear antibody was elevated. After a brief review of the literature the authors propose the possibility of virus-drug interaction as a model of adverse drug reactions. © 2004 European Academy of Dermatology and Venereology.