Placental lakes, absent umbilical artery diastolic flow and poor fetal growth in early pregnancy

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Abstract

Uteroplacental insufficiency is a common cause of intrauterine growth retardation in the third trimester of pregnancy. We report a case in which placental vascular lesions, absent end-diastolic frequencies in the umbilical artery and high maternal serum levels of α-fetoprotein and human chorionic gonadotropin were observed from the beginning of the second trimester in a patient with a history of recurrent first- and second-trimester miscarriages. Fetal growth started to slow down from 14 weeks of gestation and no end-diastolic phase was found in the umbilical artery until 18 weeks of gestation, when the pregnancy was terminated. In apparently healthy women with or without a history of fetal death during the first half of pregnancy, the discovery of placental vascular lesions together with a high resistance to blood flow in the umbilical circulation should prompt early antepartum surveillance.

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Jauniaux, E. (1996). Placental lakes, absent umbilical artery diastolic flow and poor fetal growth in early pregnancy. Ultrasound in Obstetrics and Gynecology, 7(2), 141–144. https://doi.org/10.1046/j.1469-0705.1996.07020141.x

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