Comparative Study of 3rd Generation V/S 4th Generation ELISA in Blood Donors for Early Diagnosis of HIV in Rural Population

Abstract

The present study has been conducted in the rural population attended to MNR medical college for blood donation. Among the 100 voluntary donors screened for HIV the mean age group being taken 19 to 50 yrs. Among the gender the male donors were more in number. The first Screening test for detecting HIV infection is the third-generation ELISA 3 rd (GENERATION ELISA TEST) IVD used to screen blood donors for HIV infection proved to be 100% sensitive, and 100% specific for the detection of Abs to HIV-1 and HIV-2. The fourth-generation ELISA (Erbasure 4th generation) also showed 100% Sensitivity and Specificity for Antibody detection. However, it was able to detect p24 Ag.