A platform for quantifying atrial structural remodelling

Abstract

Cross sectional imaging tools are increasingly used prior to cardiac electrophysiology procedures. Cardiac Magnetic Resonance (CMR) imaging provides detailed anatomic information that can quantify structural remodelling of the atrial chambers. Atrial Late Gadolinium Enhanced (LGE) CMR may be used to identify fibrotic change in the atrium. A standardised and transparent approach to the analysis of CMR imaging would facilitate a broader applicability of such tools for complex image analysis. Furthermore, an assessment of the utility of such tools beyond highly specialised centres would be possible. In this paper, we introduce an open source platform, provide standardised solutions for extracting information from clinical images, and propose standard definitions of the atrial anatomy for comparing clinical indices.