The protein array is a powerful platform to study humoral responses to infectious agents using small sample volumes [<3 μL]. Its success can be largely attributed to the development of new strategies for high-throughput cloning and expression, and improved manufacturing techniques for the construction of arrays. Here, we describe a method to hybridize protein arrays with malaria patients’ sera in order to identify seroreactive antigens, some of which may have a high potential of conferring protection from severe forms of malaria.
CITATION STYLE
Venkatesh, A., Jain, A., Davies, H., Felgner, P. L., Rathod, P. K., Patankar, S., & Srivastava, S. (2021). Protein Arrays for the Identification of Seroreactive Protein Markers for Infectious Diseases. In Methods in Molecular Biology (Vol. 2344, pp. 139–150). Humana Press Inc. https://doi.org/10.1007/978-1-0716-1562-1_10
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