Neuroendocrine tumors of the appendix

Abstract

OBJECTIVE: Appendicle carcinoid tumors are part of neuroendocrine tumors. The carcinoid tumor is most frequent off all appendicle tumors and it is generally observed in females in her 60s. METHOD: It is reported 2 cases of male patients with acute appendicitis clinical symptoms whom was performed no laparoscopic appendectomy whose biopsies reported carcinoid tumor, visualized microscopically only. They were located at edge and also invaded the serosa. When immunohistochemistry was done they were classified as neuroendocrine tumor grade 1 following the diagnosis of WHO classification. RESULTS: Treatment indicated in both cases due to the characteristics of the tumors is the appendectomy; which was done previous diagnosis as usual. The diagnostic is generally done by chance at the moment of de analysis of the anatomopatologic studies of the sample sent for specific studies. All appendicle carcinoid tumors have to be removing. The extension studies showed findings within normal limits. None of patients presented clinical symptoms related to carcinoid syndrome for their diagnosis. Nowadays it is known its malignant potential and they are considered malignant neoplasia. CONCLUSIONS: Prognosis and survival of these tumors is satisfactory. Generally the evolution of these tumors is satisfactory and with no evidence of recurrence.