Regioselective ring opening of epoxides with amines using Silica-bonded S-sulfonic acid under solvent-free conditions

Abstract

Silica-bonded S-sulfonic acid (SBSSA) was used as a recyclable and reusable catalyst for the synthesis of β-amino alcohols. Several amines were reacted with epoxides to afford regioselective β-amino alcohols in high yield under solvent-free conditions at room temperature. © 2012, Sociedad Química de México.