The transgenerational effects of parental exposure to mutagens in mammals

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Abstract

The review describes the transgenerational effects of parental exposure to ionizing radiation, chemical mutagens and anticancer drugs. The results of some recent animal studies showing elevated mutation rates in the non-exposed offspring of irradiated parents are presented and discussed. The possible mechanisms and implications of transgenerational instability are also discussed.

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Dubrova, Y. E. (2013). The transgenerational effects of parental exposure to mutagens in mammals. In Stress-Induced Mutagenesis (pp. 243–255). Springer New York. https://doi.org/10.1007/978-1-4614-6280-4_12

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