Indications for Laboratory Tests for Toxoplasmosis

Abstract

It is suggested that tests for toxoplasmosis should be performed in cases of lymphadenopathy of uncertain aetiology, chloroidoretinitis, and neonatal illness with hydrocephalus, meningeal symptoms, or generalized illness with hepatosplenomegaly. Toxoplasmosis is rarely the cause of encephalitis, myocarditis, or pneumonia ; but in atypical cases, where the aetiology remains in doubt, tests may be worth while. A dye-test titre of 1/512 or higher is presumptive evidence of active infection, but high titres may occur in normal persons. To prove an infection a significant rise in titre must be shown, preferably accompanied by isolation of the organism. We wish to thank Professors C. P. Beattie and E. S. Perkins for allowing us the benefit of their great experience while preparing this memorandum. © 1965, British Medical Journal Publishing Group. All rights reserved.