Hypertrophic pachymeningits is an unusual cause of neurological symptoms and is often secondary to infections, carcinomatosis or inflammatory diseases. It may also be idiopathic. We report a case of pachymeningitis which was manifested primarily by psychosis and visual loss with optic atrophy and destruction of nasal septum. The patient, a 45 year old woman was submitted to extensive investigation without evidence of any underlying disease. A meningeal biopsy was performed and showed a mostly unspecific inflammatory process with extensive fibrosis of the dura and few early stage granulomas. These findings suggest either neurosarcoidosis or idiopathic hypertrophic pachymeningitis.
CITATION STYLE
De Deus-Silva, L., De Souza Queiroz, L., De Araújo Zanardi, V., Ghizoni, E., Da Costa Pereira, H., Silva Malveira, G. L., … Cendes, F. (2003). Hypertrophic pachymeningitis: Case report. Arquivos de Neuro-Psiquiatria, 61(1), 107–111. https://doi.org/10.1590/s0004-282x2003000100021
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