Introduction: Obsessive-compulsive disorder is defined by the presence of obsessions and compulsions that cause marked anxiety or distress and has been associated with a disruption in cortico-striato-thalamo-cortical circuitry. After treatment, around 50% of patients continue to experience incapacitating symptoms. Deep-brain stimulation has been shown to be an effective therapeutic alternative to regular treatment. Methods: Case report. Case presentation: A 54-year-old woman with a diagnosis of treatment-resistant obsessive-compulsive disorder was treated with deep-brain stimulation of the anterior limb of the internal capsule. Molecular imaging before and after the procedure was obtained and correlated with clinical features. Conclusions: Deep-brain stimulation may be a therapeutic alternative to regular care in treatment-resistant obsessive-compulsive disorder and can be correlated to functional changes in suspected anatomical structures.
CITATION STYLE
Oñate-Cadena, N., Cisneros-Otero, M., Ruiz-Chow, Á. A., Arellano-Reynoso, A., Kobayashi-Romero, L. F., & Pérez-Esparza, R. (2020). Deep-brain stimulation in treatment-resistant obsessive-compulsive disorder: Clinical and molecular neuroimaging correlation. Revista Colombiana de Psiquiatria, 49(1), 62–65. https://doi.org/10.1016/j.rcp.2018.05.002
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