PET image reconstruction: Methodology and quantitative accuracy

Abstract

This chapter reviews the techniques developed for positron emission tomography (PET) image reconstruction and image property analysis. Both mathematical theory and practical considerations are introduced. We focus on the commonly used methods on commercial PET scanners, in particular model-based statistical reconstruction methods. We also briefly describe data corrections necessary for PET image reconstruction, which are important for reducing artifacts and improving quantitative accuracy. Finally some recent developments are described, including the reconstruction of time-of-flight (TOF) PET data and direct parametric image reconstruction.