Membranes are protein and lipid structures that surround cells and other biological compartments. We present a conceptual model wherein all membranes are organized into structural and functional zones. The assembly of zones such as receptor clusters, protein-coated pits, lamellipodia, cell junctions, and membrane fusion sites is explained to occur through a protein-lipid code. This challenges the theory that lipids sort proteins after forming stable membrane subregions independently of proteins.
CITATION STYLE
Kervin, T. A., & Overduin, M. (2024). Membranes are functionalized by a proteolipid code. BMC Biology, 22(1). https://doi.org/10.1186/s12915-024-01849-6
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