Cell Engineering of the Rat and Human Cysteine Conjugate Beta Lyase Genes and Applications to Nephrotoxicity Assessment

  • Gibson G
  • Goldfarb P
  • King L
  • et al.
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Abstract

... Figure 10. Concurrent transamination and beta lyase activities. enzyme by transamination . The cellular supply of the appropriate alpha-keto acids are obiously limited and at relatively low concentrations and the transaminase reaction would therefore gradually switch off. ...

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Gibson, G. G., Goldfarb, P. S., King, L. J., Kitchen, I., Plant, N., Scholfield, C., & Harries, H. (1999). Cell Engineering of the Rat and Human Cysteine Conjugate Beta Lyase Genes and Applications to Nephrotoxicity Assessment. In Molecular and Applied Aspects of Oxidative Drug Metabolizing Enzymes (pp. 283–291). Springer US. https://doi.org/10.1007/978-1-4615-4855-3_20

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