Acinar cell carcinoma of the pancreas with and without endocrine differentiation

14Citations
Citations of this article
15Readers
Mendeley users who have this article in their library.

Abstract

Background: Acinar cell carcinoma (ACC) is a rare pancreatic neoplasm, representing 1% of exocrine tumours and containing a variable endocrine component. Three recent cases of ACC are reported. Case outlines: A 72-year-old man with painless obstructive jaundice had a 5-cm mass in the head of pancreas resected by Whipple's operation; histopathological examination showed a typical ACC. A 33-year-old man with weight loss and abnormal liver function had a dilated biliary tree but no mass on imaging. Pylorus-preserving pancreatoduodenectomy was performed, and histology showed a mixed acinar-neuroendocrine tumour. A 56-year-old man with weight loss and a palpable mass had a 15-cm mass in the distal body of pancreas, which was resected en bloc with the spleen and adherent stomach; it was a cystic ACC. Results: Two patients are alive and free of disease at 30 months and 15 months, while the third patient with locally advanced disease died of myocardial infarction at 9 weeks. Discussion: Acinar structures are the hallmark of this neoplasm, which carries a better survival rate than ductal cancer. Surgical excision prolongs survival and offers the best chance of cure.

Figures

References Powered by Scopus

Pancreatic cancer: A report of treatment and survival trends for 100,313 patients diagnosed from 1985-1995, using the National Cancer Database

758Citations
N/AReaders
Get full text

Acinar cell carcinoma of the pancreas: A clinicopathologic study of 28 cases

457Citations
N/AReaders
Get full text

Exocrine pancreatic tumours and their histological classification. A study based on 167 autopsy and 97 surgical cases

253Citations
N/AReaders
Get full text

Cited by Powered by Scopus

Pancreatic acinar cell carcinoma: A review on molecular profiling of patient tumors

55Citations
N/AReaders
Get full text

Mixed acinar-endocrine carcinoma of the pancreas: New clinical and pathological features in a contemporary series

32Citations
N/AReaders
Get full text

Mixed acinar-endocrine carcinoma of the pancreas: A case report and review of the literature

25Citations
N/AReaders
Get full text

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Cite

CITATION STYLE

APA

Virlos, I. T., Papazachariou, I. M., & Williamson, R. C. N. (2002). Acinar cell carcinoma of the pancreas with and without endocrine differentiation. HPB, 4(2), 87–90. https://doi.org/10.1080/136518202760378452

Readers over time

‘13‘15‘16‘17‘18‘19‘20‘21‘22‘2300.751.52.253

Readers' Seniority

Tooltip

PhD / Post grad / Masters / Doc 9

75%

Researcher 2

17%

Professor / Associate Prof. 1

8%

Readers' Discipline

Tooltip

Medicine and Dentistry 8

67%

Biochemistry, Genetics and Molecular Bi... 2

17%

Social Sciences 1

8%

Agricultural and Biological Sciences 1

8%

Save time finding and organizing research with Mendeley

Sign up for free
0