Serological, culture and urea breath test for detection of h. Pylori in gastric ulcers patients

Abstract

Helicobacter pylori t is the causative agent of duodenal ulcers and gastric ulcers, thus, it is very important to determine the most appropriate system used to diagnose it. The current study use invasive and noninvasive process for diagnosis of H. pylori. Culture of H. pylori is one of these invasive systems, and the results revealed that 35% of specimen was culture positive (62.5% in male and 37.5 in female) While, the non-invasive method like UBT and ELISA IgG and IgA show 67.1% and 71.5%, 29.2% positive results respectively. The distribution of positive test results between male and female by UBT was (41.3%) male and (58.7%) female) while, the distribution of positive test results between male and female by ELISA IgG and IgA were (61.4%), (26.3%) in male patients and (78.75%), (31.25%) in female patients respectively. The results of UBT were increase with age, (34 positive patients in age group 51-60 years old). Serological test of ELISA IgG shows that great % of H. pylori infection (74%) found in patients with group age (41-50) yr.O. and the lowest percentage (39%) was found with age group (<20) years old while, percentages of positive cases of ELISA IgA in young age below 20 years old was 79% related to low % with ages increase.