Cancer gene silencing without DNA hypermethylation.

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Abstract

Both DNA hypermethylation and Polycomb-mediated histone methylation induce gene silencing in cancer, but largely in two separate paths. Hence, different pharmacologic approaches are required to reactivate genes silenced by distinct epigenetic mechanisms.

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APA

Yu, Q. (2008). Cancer gene silencing without DNA hypermethylation. Epigenetics : Official Journal of the DNA Methylation Society, 3(6), 315–317. https://doi.org/10.4161/epi.3.6.7202

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