Abstract
Thirty-five patients (19 male and 16 female) with clinically definite multiple sclerosis and 100 healthy control subjects were studied for the A and B locus of the HLA system. A significant increase of HLA A3 and Al1 of the A locus and B7 of the B locus was observed in patients with multiple sclerosis compared with controls. An increase of antigen A3 was also observed in eight cases of probable multiple sclerosis. A significant increase of both A3 and B7 was observed in patients with multiple sclerosis.
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CITATION STYLE
Lotfi, J., Nikbin, B., Derakhshan, I., Aghai, Z., & Ala, F. (1978). Histocompatibility antigens (HLA) in multiple sclerosis in Iran. Journal of Neurology, Neurosurgery and Psychiatry, 41(8), 699–701. https://doi.org/10.1136/jnnp.41.8.699
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