Single Molecule Imaging Using X-ray Free Electron Lasers

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Abstract

The potential to image single molecules in action with a resolution sufficiently high to reveal atomic information at room temperature without the need for crystallization is one of the most exciting applications of X-ray free electron lasers. Significant progress has been made towards this goal over the past years. Here we discuss the current status and describe the steps still required to realize atomic resolution X-ray single particle imaging.

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Aquila, A., & Barty, A. (2018). Single Molecule Imaging Using X-ray Free Electron Lasers. In X-ray Free Electron Lasers: A Revolution in Structural Biology (pp. 401–426). Springer International Publishing. https://doi.org/10.1007/978-3-030-00551-1_14

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