Impact of oxygenation status on18F-FDG uptake in solid tumors

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Abstract

The influence of changes in tumor oxygenation (monitored by EPR oximetry) on the uptake of18F-FDG tracer was evaluated using micro-PET in two different human tumor models. The18F-FDG uptake was higher in hypoxic tumors compared to tumors that present a pO2 value larger than 10 mmHg.

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Neveu, M. A., Bol, V., Bol, A., Grégoire, V., & Gallez, B. (2016). Impact of oxygenation status on18F-FDG uptake in solid tumors. In Advances in Experimental Medicine and Biology (Vol. 876, pp. 201–207). Springer New York LLC. https://doi.org/10.1007/978-1-4939-3023-4_25

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