Diffuse large B-cell lymphoma often presents with extranodal manifestations involving the musculoskeletal system. Shoulder pain is particularly worrisome for malignancy. Individuals presenting with refractory upper extremity complaints should undergo a prompt and thorough evaluation for cancer, as a delay in diagnosis can result in an unfavorable outcome.
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Beutler, B. D., Krishan, R., Parafianowicz, P., Ulanja, M. B., Elliott, C., France, J., … Gullapalli, N. (2020). ABC-type diffuse large B-cell lymphoma presenting as rotator cuff tendinopathy: A diagnostic dilemma and review of the literature. Clinical Case Reports, 8(2), 327–332. https://doi.org/10.1002/ccr3.2630
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