Gastric bypass and alcohol use: A literature review

Abstract

Background: Obesity is public health issue; bariatric surgery is considered as the most efficient treatment. However, the risk of developing an alcohol use disorder could increase after Roux-en-Y bypass. The purpose of this review is to emphasize the further research needed in this area. Methods: Pubmed and Sciencedirect databases were searched. Articles written in another language than French or English as well as abstracts, conference presentations, editorials and expert opinions were excluded. Results: Most of studies included in this review show an increased risk of developing an AUD (alcohol use disorder) after gastric bypass surgery. Male sex, younger age, smoking, regular alcohol consumption, AUD, recreational drug use, lower sense of belonging and undergoing a RYGB (Roux-en-Y gastric bypass) were identified as risk factors. There is an alteration of alcohol metabolism after gastric bypass. Gut hormones could also play a role in the development of AUD. The hypothesis of an addiction transfer is still controversial. Conclusions: The risk of developing an AUD seems to increase after surgery. Long term follow-up, after the second post-surgery year, is needed. Further researches are needed to understand the mechanisms that underlie the development of AUD.