Pentazocine-induced neuromuscular syndromes: clinical, immunological and histopathological studies in two cases.

Abstract

Two cases of pentazocine-induced neuromuscular syndrome in addicted patients are reported. Histochemical and quantitative histographic analyses of muscle biopsies performed in areas distant from site of injection, disclosed type 2 atrophy. A generalized myotoxic effect of pentazocine is suggested.