0851 Sleep Duration and Asthma Outcomes in Adolescents

Abstract

Introduction: Asthma is the most common pediatric chronic illness, impacting approximately 10% of adolescents. There is a need to examine modifiable behaviors, such as sleep duration, which may reduce the morbidity of asthma (e.g., missed school days). Using an established sleep‐manipulation protocol, this study examined the impact of sleep duration on objective and subjective measures of lung function. Methods: Fifty‐four adolescents (68.5% female; 66.7% White; 25.9% Hispanic; mean age=14.7 years) completed a 3‐week randomized, cross‐over protocol. Following a week of sleep stabilization, adolescents were randomized to 5 nights of insufficient (short) sleep opportunity (6.5 hrs in bed) and healthy (long) sleep opportunity (9.5 hrs in bed). Wake time remained consistent across all three weeks. Participants completed daily peak expiratory flow rates (PEFR) within 30 minutes of waking and 12 hours later, weekly spirometry and exhaled nitric oxide (eNO), and the PROMIS Asthma Impact Scale. Results: For peak flow meter data, a significant overnight mean change in FEV1 was found for the short week (82 mL decrease, p=.004), but not the long week (24 mL decrease, p=.45). A significant overnight change was also found in PEFR for both the short and long weeks (p=