A computing model for four-valued logic AND gate based on DNA origami and DNA displacement

Abstract

A four-valued logic AND gate model is constructed by DNA origami and DNA strand displacement. Different input signals are designed into different input DNA strands, the results of the input signals are determined by observing whether the hairpin structures are unwound (the length of the long strand is changed) and the fluorescence colors are quenching. The biological expectation results show that the model can not only judge the false and true states of the four valued logic AND gate, other states in four-valued logic AND gate can also be well displayed by the long strand length changed and fluorescence quenching.