Bradykinin receptors on normal lung membranes seem to be coupled to adenylate cyclase. Stimulation of the enzyme from sensitized lung membranes by adrenaline and vasoactive intestinal peptide was markedly reduced, whereas the ability of bradykinin and histamine to activate the sensitized adenylate cyclase was unaffected. Additional experiments are necessary in order to delineate the precise molecular events associated with activation of each of the two presently known bradykinin receptor types.
CITATION STYLE
Gadd, A. L., & Bhoola, K. (1986). Activation by bradykinin and vasoactive intestinal peptide of adenylate cyclase from immunologically sensitized lung membranes. Advances in Experimental Medicine and Biology, 198 Pt A, 577–583. https://doi.org/10.1007/978-1-4684-5143-6_77
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