The shape of anodal strength-interval curves and make and break excitation mechanisms are investigated in a 2D anisotropic Bidomain model, with different membrane models and action potential durations, and in a 3D rotational anisotropic Bidomain model, with axisymmetric or orthotropic conductivity properties. The results have shown that the LRd model with a long intrinsic APD exhibits a systolic dip threshold lower than the diastolic threshold, in agreement with previous experimental data. The spatial and temporal analysis of the excitation patterns indicates a novel anode make excitation mechanism with delayed propagation within the transition from break to make mechanisms. © 2011 Springer-Verlag Berlin Heidelberg.
CITATION STYLE
Colli-Franzone, P., Pavarino, L. F., & Scacchi, S. (2011). Anode make and break excitation mechanisms and strength-interval curves: Bidomain simulations in 3D rotational anisotropy. In Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics) (Vol. 6666 LNCS, pp. 1–10). https://doi.org/10.1007/978-3-642-21028-0_1
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