COVID-19 vaccine utilizing the technology of gene therapy

Abstract

The successful rapid development of mRNA vaccines against COVID-19 reaffirms the importance of vaccines against emerging infectious diseases. Many SARS-CoV-2 vaccine target antigens that have been developed are viral surface spike proteins that elicit an immune response, inducing neutralizing antibodies and activating cell-mediated immunity. The major feature of the COVID-19 vaccine is that it has been used as a viral vector vaccine and mRNA / DNA vaccine using gene therapy technology. Among them, the mRNA vaccine has been successfully developed most rapidly.