The COVID-19 pandemic has posed a serious problem for drug anti-viral efficacy in combatting the cytokine storm triggered by SARS-CoV-2. From dermato-epidemiological studies conducted on psoriatic and other rheumatological patients, IL-17 inhibitors seem to attenuate or even prevent the cytokine storm and thus ICU referral. Furthermore, both invivo and in-vitro experiments suggest that IL-17 plays a key role in SARS-CoV-2 infection progression. Due to this evidence, we decided to summarize the literature findings on IL-17 inhibitors and COVID-19, maintaining psoriasis as the referral disease to better understand the extent of drug effects on the immune system.
CITATION STYLE
Zou, Y., & Meng, Z. (2021). Literature overview of the IL-17 inhibition from psoriasis to COVID-19. Journal of Inflammation Research. Dove Medical Press Ltd. https://doi.org/10.2147/JIR.S329252
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