Anaplastic solitary plasmacytoma of mandible, masquerading as sarcoma

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Abstract

Plasma cell neoplasm is characterized by a monoclonal neoplastic proliferation of plasma cells and solitary plasmocytoma of bone (SPB) is a localized form. It usually occurs in vertebrae and secondarily in long bones. Its presence in mandible is extremely rare event. A 48-year-old man consulted to our clinic with a chief complaint of pain in his mandible. Radiography revealed a destructive lesion in body and ramus. The initial pathologic evaluation revealed a high grade pleomorphic neoplasm. The diagnosis was confirmed by immunohistochemical markers. Overall, plasmacytoma with anaplastic features can be confused with high grade sarcoma clinically and histologically.

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Javad Ashraf, M., Azarpira, N., & Khademi, B. (2013). Anaplastic solitary plasmacytoma of mandible, masquerading as sarcoma. Pakistan Journal of Medical Sciences, 29(3). https://doi.org/10.12669/pjms.293.3406

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