A short history of cGMP, guanylyl cyclases, and cGMP-dependent protein kinases

Abstract

Here, we review the early studies on cGMP, guanylyl cyclases, and cGMP-dependent protein kinases to facilitate understanding of development of this exciting but complex field of research encompassing pharmacology, biochemistry, physiology, and molecular biology of these important regulatory molecules. © 2009 Springer Berlin Heidelberg.