Studying the effect of hydroxyapatite particles in osteoconductivity of Ti-HA bioceramic

Abstract

Ball milling method and powder metallurgy technology were employed to synthetize metal matrix composites (MMC) for bone grafts’ applications. The raw powder of the MMC was prepared by mechanical alloying of pure titanium (Ti) powder with hydroxyapatite (HA) particles. The biocompatibilities of the sintered Ti-HA composites were examined after immersing the samples in simulated body solution (SBF) for different periods of time. SEM image and XRD results analysis were utilized to study the effect of HA on osteoconductivity of the Ti-HA composite. To this purpose, several composites were synthetized from different Ti-HA raw powder combination based on the HA particle size, milling time, and the mass fraction of HA content (% w/w) in the MMC. In vitro analysis of Ti-HA composite shows that composite with 30% w/w HA has higher bioactivity in comparison with composite containing pure Ti with 10% w/w HA.