A clinical and microbiological evaluation of Helicobacter pylori in recurrent aphthous stomatitis

Abstract

Aim: The aim of this study is to evaluate the association of Helicobacter pylori in recurrent aphthous stomatitis (RAS) with or without peptic ulcer. Materials and methods: A total of 42 patients were selected for the present study from outpatient Department of Oral Medicine, and divided into control (group I) and test groups (groups II, III). A total number of 15 patients suffering from RAS based on history and clinical examination was selected as group II. A total number of 12 patients suffering concomitantly from RAS and duodenal ulcer based on history and clinical examination were selected as group III. A total number of 15 healthy subjects were selected as controls in group I. All selected subjects belonged to the age group of 16 to 45 years. Data were tabulated and statistically analyzed with Statistical Package for the Social Sciences (SPSS) statistical software version 19 of IBM, Chicago, Illinois, USA. Results: Among all three groups, 54.8% was negative and 45.2% was positive for H. pylori. No significant relation was established between H. pylori and RAS. Conclusion: In the present study, there was no association of H. pylori in patients with RAS and in patients with RAS along with gastric ulcers. Clinical significance: This clinical study evaluated the relation of H. pylori in RAS patients.