Comorbidity of primary torsion dystonia with psychiatric disorders

Abstract

The authors investigate and describe comorbidity of PTD with psychiatric diseases reviewing the medical records of all hospitalized patients, diagnosed with PTD for a period of four years. 75 patients with confirmed diagnose of PTD gave their informed consent and were clinically investigated including an examination by a specialist psychiatrist. The majority of the patients with the psychiatric comorbidity experience depressive symptoms, but more importantly a high percent of the patients (4%) suffer from schizophrenia. Therefore one can assume that there is an abnormality in the common cerebellar pathways in the brain in PTD and schizophrenia.