Abstract
This case discusses a drug-gene interaction. Promethazine is a cytochrome P450 (CYP) 2D6 substrate. Patients who are CYP2D6 poor metabolizers exhibit greater sedation for a given promethazine dose.
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CITATION STYLE
APA
Wittwer, E. D., Sprung, J., & Nicholson, W. T. (2015). Predisposed to doze: Promethazine, CYP2D6 poor metabolizer. In A Case Approach to Perioperative Drug-Drug Interactions (pp. 401–403). Springer New York. https://doi.org/10.1007/978-1-4614-7495-1_86
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