Vegetable diversity, injurious falls, and fracture risk in older women: A prospective cohort study

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Abstract

The importance of vegetable diversity for the risk of falling and fractures is unclear. Our objective was to examine the relationship between vegetable diversity with injurious falling and fractures leading to hospitalization in a prospective cohort of older Australian women (n = 1429, ≥70 years). Vegetable diversity was quantified by assessing the number of different vegetables consumed daily. Vegetable intake (75 g servings/day) was estimated using a validated food frequency questionnaire at baseline (1998). Over 14.5 years, injurious falls (events = 568, 39.7%), and fractures (events = 404, 28.3%) were captured using linked health records. In multivariable-adjusted Cox regression models, women with greater vegetable diversity (per increase in one different vegetable/day) had lower relative hazards for falls (8%; p = 0.02) and fractures (9%; p = 0.03). A significant interaction between daily vegetable diversity (number/day) and total vegetable intake (75 g servings/day) was observed for falls (pinteraction = 0.03) and fractures (pinteraction < 0.001). The largest benefit of higher vegetable diversity were observed in the one third of women with the lowest vegetable intake (<2.2 servings/day; falls HR 0.83 95% CI (0.71–0.98); fractures HR 0.74 95% CI (0.62–0.89)). Increasing vegetable diversity especially in older women with low vegetable intake may be an effective way to reduce injurious fall and fracture risk.

Figures

  • Table 1. Baseline characteristics according to all participants and by vegetable diversity intake categories.
  • Figure 1. Kaplan-Meier survival curves for vegetable diversity categories for (a) injurious falls and (b) fractures over 14.5 years. Low (≤3 number/d), moderate (4 number/d), and high (≥5 number/d) vegetable diversity categories are represented by the black, light grey, and grey lines, respectively.
  • Figure 2. Age-adjusted hazard ratios for injurious falls and fractures based on categories of (a) vegetable intake and (b) vegetable diversity over 14.5 years. Categories for vegetable intake included: low <2.2 s/d (n = 476), moderate 2.2 to <2.9 s/d (n = 477) and high ≥2.9 s/d (n = 476). Categories for vegetable diversity included: low <4 n/d (n = 484), moderate 4 n/d (n = 440), and high ≥5 n/d (n = 505). Overall interaction for vegetable intake (s/d) and vegetable diversity (n/d) was pinteraction = 0.03 and pinteraction < 0.001 for injurious falls and fractures, respectively. n/d = number/day; s/d = servings/day.

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CITATION STYLE

APA

Sim, M., Blekkenhorst, L. C., Lewis, J. R., Bondonno, C. P., Devine, A., Zhu, K., … Hodgson, J. M. (2018). Vegetable diversity, injurious falls, and fracture risk in older women: A prospective cohort study. Nutrients, 10(8). https://doi.org/10.3390/nu10081081

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