Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy

59Citations
Citations of this article
92Readers
Mendeley users who have this article in their library.

This article is free to access.

Abstract

BackgroundDexamethasone has a powerful anti-inflammatory action and has demonstrated reduced morbidity after surgery. The aim of this study was to examine the effects of a single i.v. dose of dexamethasone in combination with caudal block on postoperative analgesia in children.MethodsSeventy-seven children (aged 1-5 yr) undergoing day-case orchiopexy were included in this prospective, randomized, double-blinded study at a single university hospital. After inhalation induction of general anaesthesia, children received either dexamethasone 0.5 mg kg-1 (maximum 10 mg) (n=39) or the same volume of saline (n=38) i.v. A caudal anaesthetic block was then performed using 1.5 ml kg-1 of ropivacaine 0.15 in all patients. After surgery, rescue analgesic consumption, pain scores, and adverse effects were evaluated for 24 h.ResultsSignificantly, fewer patients in the dexamethasone group required fentanyl for rescue analgesia (7.9 vs 38.5) in the post-anaesthetic care unit or acetaminophen (23.7 vs 64.1) after discharge compared with the control group. The time to first administration of oral acetaminophen was significantly longer in the dexamethasone group (646 vs 430 min). Postoperative pain scores were lower in the dexamethasone group and the incidence of adverse effects was similar in both groups.ConclusionsIntravenous dexamethasone 0.5 mg kg -1 in combination with a caudal block augmented the intensity and duration of postoperative analgesia without adverse effects in children undergoing day-case paediatric orchiopexy.Trial registration: ClinicalTrials.gov. The number of registration: NCT01041378. © The Author 2010. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved.

Cite

CITATION STYLE

APA

Hong, J. Y., Han, S. W., Kim, W. O., Kim, E. J., & Kil, H. K. (2010). Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy. British Journal of Anaesthesia, 105(4), 506–510. https://doi.org/10.1093/bja/aeq187

Register to see more suggestions

Mendeley helps you to discover research relevant for your work.

Already have an account?

Save time finding and organizing research with Mendeley

Sign up for free