ChAMP: 450k Chip Analysis Methylation Pipeline

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Abstract

The Illumina Infinium HumanMethylation450 BeadChip is a new platform for high-throughput DNA methylation analysis. Several methods for normalization and processing of these data have been published recently. Here we present an integrated analysis pipeline offering a choice of the most popular normalization methods while also introducing new methods for calling differentially methylated regions and detecting copy number aberrations. © 2013 The Author 2013.

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Morris, T. J., Butcher, L. M., Feber, A., Teschendorff, A. E., Chakravarthy, A. R., Wojdacz, T. K., & Beck, S. (2014). ChAMP: 450k Chip Analysis Methylation Pipeline. Bioinformatics, 30(3), 428–430. https://doi.org/10.1093/bioinformatics/btt684

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