1,3,4-thiadiazole derivatives. Part 9. Synthesis and biological activity of metal complexes of 5-(2-aminoethyl)-2-amino-1,3,4-thiadiazole

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Abstract

Metal complexes of the title ligand (L) containing Co(II), Ni(II) and Cu(II) were prepared and characterized by elemental analysis, IR, electronic spectroscopy and conductimetry. The new derivatives, possessing the following formulae, CuL2(OH)2, NiL2Cl2, and [Co2LCl4](n) showed in vitro antifungal activity against Aspergillus and Candida spp.

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Barboiu, M., Cimpoesu, M., Guran, C., & Supuran, C. T. (1996). 1,3,4-thiadiazole derivatives. Part 9. Synthesis and biological activity of metal complexes of 5-(2-aminoethyl)-2-amino-1,3,4-thiadiazole. Metal-Based Drugs, 3(5), 227–232. https://doi.org/10.1155/MBD.1996.227

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