The history, characteristic, operation modes and coupling techniques of atomic force microscopy (AFM) are introduced. Then the application in cell biology is reviewed in four aspects: cell immobilization methods, cell imaging, force spectrum study and cell manipulation. And the prospect of AFM application in cell biology is discussed.
CITATION STYLE
Deng, S.-P., Yang, Y.-L., Cheng, X.-X., Li, W.-R., & Cai, J. (2018). In Situ Measuring Mechanical Properties of Normal and Disease Cells. In Atomic Force Microscopy in Molecular and Cell Biology (pp. 161–178). Springer Singapore. https://doi.org/10.1007/978-981-13-1510-7_9
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