Chromosome components important for genome stability in candida albicans and related species

Abstract

Pathogenic microorganisms have been constantly evolving to battle the various responses elicited by the host upon their invasion. Candida albicans bears no exception to this trend. It is not only a fitter pathogen but also a successful gut commensal in humans. The extraordinary genome plasticity of C. albicans makes its survival possible in such widely diverse host niches. This chapter focuses on various chromosomal elements that are involved in maintaining the genome dynamics and stability in C. albicans. Here, we discuss molecular players of the basic cellular processes that lead to duplication of chromosomes, their faithful segregation in progeny, and chromosome maintenance in C. albicans and its related species.