Synthesis of (−)-Cannabimovone and Structural Reassignment of Anhydrocannabimovone through Gold(I)-Catalyzed Cycloisomerization

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Abstract

The first total synthesis of cannabimovone from Cannabis sativa and anhydrocannabimovone was achieved by means of a highly stereoselective gold(I)-catalyzed cycloisomerization. The results led to reassignment of the structure of anhydrocannabimovone.

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Carreras, J., Kirillova, M. S., & Echavarren, A. M. (2016). Synthesis of (−)-Cannabimovone and Structural Reassignment of Anhydrocannabimovone through Gold(I)-Catalyzed Cycloisomerization. Angewandte Chemie - International Edition, 55(25), 7121–7125. https://doi.org/10.1002/anie.201601834

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