Conclusions

Abstract

We now have a diverse menu of osteoporosis therapies with proven efficacy in randomized clinical trials. As we individualize therapies for our patients, we need to base our decisions not only on efficacy but safety and adherence. However, this is challenging given that there are major limitations to the evidence base for long-term treatment and for use of drug holidays. This book and with its 23 chapters is a starting point for the clinician to understand the challenges of both short- and long-term safety concerns, adherence, and duration of therapies.