EAE: History, clinical signs, and disease course

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Abstract

EAE is a useful animal model of autoimmune disease of the central nervous system. In this chapter we discuss the history of EAE, including the original description of the model and the subsequent major developments, and then describe the usual clinical signs and disease course.

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William Lindsey, J. (2005). EAE: History, clinical signs, and disease course. In Experimental Models of Multiple Sclerosis (pp. 1–9). Springer US. https://doi.org/10.1007/0-387-25518-4_1

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