Long-chain polyunsaturated fatty acids (LC-PUFA) accretion (essential for growth and neural development) was studied from late fetal throughout weaning age in the ferret, a species with maternal LC-PUFA sufficiency during pregnancy and lactation. The data show that a) accretion rate of LC-PUFA is rapid during early postnatal development, b) milk LC-PUFA decrease during lactation, c) adipose tissue LC-PUFA level is directly related to milk LC-PUFA level, while accretion in brain and liver exceeds dietary intake, d) accretion of arachidonic acid occurs earlier than docosahexaenoic acid, suggesting earlier development of n6-fatty acid endogenous synthesis.
CITATION STYLE
Hamosh, M., Henderson, T. R., Kemper, M. A., Orr, N. M., Gil, A., & Hamosh, P. (2001). Long-chain polyunsaturated fatty acids (LC-PUFA) during early development: Contribution of milk LC-PUFA to accretion rates varies among organs. Advances in Experimental Medicine and Biology, 501, 397–401. https://doi.org/10.1007/978-1-4615-1371-1_49
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