Steroid responsive encephalopathy in cerebral amyloid angiopathy: A case report and review of evidence for immunosuppressive treatment

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Abstract

Cerebral amyloid angiopathy (CAA) is a common but often asymptomatic disease, characterized by deposition of amyloid in cerebral blood vessels. We describe the successful treatment of CAA encephalopathy with dexamethasone in a patient with CAA-related inflammation causing subacute progressive encephalopathy and seizures, which is an increasingly recognized subtype of CAA. The two pathological subtypes of CAA-related inflammation are described and a review of the literature is performed concerning immunosuppressive treatment of CAA-related inflammation with special attention to its pathological subtypes. Immunosuppressive therapy appears to be an appropriate treatment for CAA encephalopathy. © 2010 Kloppenborg et al; licensee BioMed Central Ltd.

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Kloppenborg, R. P., Richard, E., Sprengers, M. E. S., Troost, D., Eikelenboom, P., & Nederkoorn, P. J. (2010). Steroid responsive encephalopathy in cerebral amyloid angiopathy: A case report and review of evidence for immunosuppressive treatment. Journal of Neuroinflammation, 7. https://doi.org/10.1186/1742-2094-7-18

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