Polymeric Micelles in Targeted Drug Delivery

Abstract

One of the most widely studied subjects in nanoscience technology is the creation of supramolecular architectures with well-defined structures and functionalities. These supramolecular structures are generated as a result of self-assembly of amphiphilic block polymers. Self-assembly of block polymers via hydrophobic and hydrophilic effects, electrostatic interactions, hydrogen bonding, and metal complexation has shown tremendous potential for creating such supramolecular structures with a wide array of applications. Polymeric micelles have gathered considerable attention in the field of drug and gene delivery due to their excellent biocompatibility, low toxicity, enhanced blood circulation time, and ability to solubilize a large number of drugs in their micellar core.