Strategies for the study of neuropsychiatric disorders using endophenotypes in developing countries: A potential databank from China

Abstract

Endophenotypic research can be considered to be one of the most promising strategies to bridge the gap between genomic complexity and the phenotypic heterogeneity observed in neuropsychiatric disorders. However, despite the promising and systematic work initiated by our western counterparts, this research strategy is still not well known in developing countries. Thus, the purpose of this paper is to argue the merits and promise of a potentially useful database on phenotypes and endophenotypes for developing countries. © 2010 Chan, Gottesman, Ge and Sham.