Elevated cTn in other acute situations such as atrial fibrillation, sepsis, respiratory failure, and gastrointestinal bleeding

Abstract

Prevalence of elevated hs-cTnT (above the 99th percentile) with relevant concentration changes in patients without an ACS is high, and elevated hs-cTn is associated with adverse long-term outcomes, irrespective the exact underlying reason. Differentiation between ischemic and non-ischemic reasons is particularly challenging as ischemic and non-ischemic mechanisms frequently co-exist. Understanding the etiology of troponin elevation in critically ill patients is important to better target appropriate therapies for MI in this population.