Anodic Oxidations of α-Santonine in Acetonitrile

Abstract

Some anodic oxidations of α-santonine using different experimental conditions were performed on a Pt electrode in acetonitrile medium. Four main products were obtained: 14-hydroxy-α-santonine, 4,5-epoxy-α-santonine, 14-acetamide-α-santonine and α-santonic acid. These oxidations were important since there are few methods to oxidize the allylic methyl groups attached to α,β-unsaturated ketones.